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Tom Riley

Dr Thomas V Riley


BAppSc Curtin, MAppEpid ANU, PhD UWA, FRCPath, MAIMS, FASM, FAAM

Professor
Microbiology & Immunology
The University of Western Australia

Principal Research Scientist
Division of Microbiology and Infectious Diseases
PathWest Laboratory Medicine WA

PRESENT APPOINTMENTS:

Professor (0.5FTE)
Microbiology & Immunology
The University of Western Australia
Queen Elizabeth II Medical Centre
Nedlands 6009 Western Australia

and

Principal Research Scientist (0.5FTE)
Division of Microbiology & Infectious Diseases
PathWest Laboratory Medicione (WA)
Queen Elizabeth II Medical Centre
Nedlands 6009 Western Australia

CURRENT RESEARCH INTERESTS:

1. Diagnosis, pathogenesis and epidemiology of Clostridium difficile-associated diarrhoea
2. The pathogenesis and epidemiology of Branhamella catarrhalis respiratory tract infections.
3. MRSA epidemiology
4. Antimicrobial activity of tea tree oil and other Australian native plants
      See homepage at http://www.tto.bcs.uwa.edu.au/
5. Erysipelothrix infections
6. Healthcare-related infection epidemiology
7. Brachyspira pilosicoli and gastrointestinal disease

MEMBERSHIP OF LEARNED SOCIETIES:

Member: American Society for Microbiology
Society for Applied Microbiology
European Society of Clinical Microbiology and Infectious Diseases
Australian Institute of Medical Scientists
Society for Anaerobic Microbiology
Anaerobe Society of the Americas
Australasian Society for Infectious Diseases
Western Pacific Society for Infectious Diseases and Chemotherapy
British Society for Antimicrobial Chemotherapy
Society of Healthcare Epidemiologists of America
Australian Epidemiological Association
Fellow: Australian Society for Microbiology
Royal College of Pathologists
American Academy of Microbiology

CURRENT EDITORIAL RESPONSIBILITIES:

International Editorial Advisory Panel member, Reviews in Medical Microbiology
Editorial Board member, Australian Infection Control
Editorial Board member, Microbiology Australia
Editor, Journal of Medical Microbiology
Editor, Clinical Microbiology & Infection
Editorial Board member, Journal of Antimicrobial Chemotherapy

COMPETITIVE RESEARCH GRANTS RECEIVED IN THE LAST 10 YEARS:

Riley, T.V., Munyard, S. Howieson, J., and Nicholls, D. 2006-10. Fisheries Industries Research & Development Corporation. Developing targeted strategies for product quality improvement in selected low value seafood supply chains. $325,769 over 3 years.

Riley, T.V., Carson, C.F., and Hammer, K.A. 2006-07. Rural Industries Research & Development Corporation. Tea tree oil to prevent staphylococcal infections in dialysis patients. $87,055.

Riley, T.V., Munyard, S. and Howieson, J. 2005-06. Fisheries Industries Research & Development Corporation. Effective sanitation for the fishing industry: using bacteriological assessment to optimise sanitiser type for processing equipment and finfish product. $37,656.

O’Donoghue, M.M., Boost, M.V., Tse, S. and Riley, T.V. 2005-06. Hong Kong Government. Determination of antimicrobial properties of traditional Chinese herbs when used alone and in combination with conventional antibiotics. HK$125,000.

Hammer, K.A., Carson, C.F. and Riley, T.V. 2005-07. Rural Industries Research & Development Corporation. Pilot study of tea tree oil in the decolonisation of MRSA positive wounds. $85,725.

Carson, C.F., Hammer, K.A. and Riley, T.V. 2005-07. Rural Industries Research & Development Corporation. Effects of tea tree oil on biofilm formation. $82,050.

Martinac, B., Riley, T.V., Wilce, M. and McKinley, A. 2005-07. National Health & Medical Research Council. Bacterial mechanosensitive channels as novel targets for antibacterial agents. $216,750 per year.

Carson, C.F., Riley, T.V., and Hammer, K.A. 2003-04. Rural Industries Research & Development Corporation. Tolerance of Pseudomonas aeruginosa to tea tree oil. $88,320.

Riley, T.V., Carson, C.F., and Hammer, K.A. 2003-04. Rural Industries Research & Development Corporation. Effects of tea tree oil on Staphylococcus aureus virulence factors. $79,888.

Riley, T.V. and Carson, C.F. 2003. Rural Industries Research & Development Corporation. Creating a database of tea tree oil related publications. $25,000.

Riley, T.V. and Carson, C.F. 2002-4. Rural Industries Research & Development Corporation. Assessing the efficacy of tea tree oil hand or body wash as a topical antiseptic. $138,765.

Lehmann, D., Riley, T.V. and Leach, A.J. 2002-4. National Health & Medical Research Council of Australia. Otitis media in Indigenous and non-Indigenous children: microbiological and immunological risk factors. $548,500.

Riley, T.V., Cadwallader, H., Inglis, T.J.J. and Plant, A. Health Department of Western Australia Interim Quality Council, 2001-2003. Reducing health-care related infections in Western Australia. $70,000.

Carson, C.F and Riley, T.V. RIRDC, 2000-2002. The antimicrobial activity of tea tree oil against oral microorganisms. $117,000

Riley, T.V., Carson, C.F. and Smith, D.W. RIRDC, 2000-2001. Clinical efficacy of tea tree oil for treating coldsores. $61,000.

Riley, T.V. and Carson, C.F. RIRDC, 2000-2001. Multi-centre randomised clinical trials of tea tree oil products for vaginal infections. $300,000.

Riley, T.V., Carson, C.F. and Hammer, K. RIRDC, 2000-2002. The antifungal activity of tea tree oil in vitro. $125,000.

Grubb, W.B., Gracey, M., Pearman, J.W. and Riley, T.V. National Health & Medical Research Council, 2000-2002. Characterisation of community methicillin-resistant Staphylococcus aureus and their control in remote communities. Approx. $100,000 per year.

Riley, T.V., Carson, C.F. and Hammer, K. RIRDC, 1999-2000. The antifungal activity of tea tree oil. $42,000.

Hart, P., Finlay-Jones, J.J., Carson, C.F. and Riley, T.V. RIRDC, 1999-2000. The anti-inflammatory activity of tea tree oil. $60,000.

Riley, T.V., Greig, J.E., Carson, C.F. and Stuckey, M.S. RIRDC, 1999-2000. Skin sensitivity testing of tea tree oil. $60,000.

Riley, T.V., Mee, B.J. and Adams, T. Fisheries Research and Development Corporation, 1999-2001. Prevention of occupationally-related infections in Western rock lobster fishermen. Approx. $70,00 per year.

Riley, T.V., Carson, C.F. and Smith, D.W. RIRDC, 1998-2000. The antiviral activity of tea tree oil. Approx. $60,000 per year.

Lehman, D., Edwards, E., Coates, H. and Riley, T.V. Healthways, 1998-2000. Risk factors for otitis media in Aboriginal and non-Aboriginal children in the Kalgoorlie area. $100,000 per year.

Hampson, D. W. Penhale, J and Riley, T.V. National Health & Medical Research Council, 1998-2000. The role of Serpulina pilosicoli as a gastrointestinal pathogen. $70,000 per year.

Riley, T.V., Carson, C.F., Hart, P. and Finlay-Jones, J.J. RIRDC, 1998-99. The anti-inflammatory activity of tea tree oil. $60,000.

Riley, T.V., Carson, C.F. and Stuckey, M.S. RIRDC, 1998-99. Skin sensitivity testing of tea tree oil. $60,000.

Porteous, J., Caelli, M. and Riley, T.V. RIRDC, 1998-2000. Tea tree oil for the decolonsation of individuals with methicillin-resistant Staphylococcus aureus. $60,000 per year.

Riley, T.V. and Carson, C.F. RIRDC, 1997-98. The antimicrobial activity of carefully extracted emu oil. $10,000.

Grubb, W.B., Gracey, M., Riley, T.V and Pearman, J.W. 1995-1997. National Health & Medical Research Council. Prevalence, origin, spread and control of MRSA in WA and Aboriginal communities. Approx. $50,000 per year.

Riley, T.V. Rural Industries Research & Development Corporation (RIRDC),1993-1996. The antimicrobial activity of tea tree oil. $60,000 per year.

CURRENT TEACHING RESPONSIBILITIES AT THE UNIVERSITY OF WESTERN AUSTRALIA:
2nd year Clinical Diagnostic Microbiology & Epidemiology
2nd year Dental Microbiology & Immunology
3rd year Infectious Disease and Immunology (medical microbiology)

RECENT PUBLICATIONS (last 5 years):

(a) Book Chapters

Chang, B.J., Mee, B.J., McGregor, K.F. and Riley, T.V. 2001. Moraxella (Branhamella) catarrhalis. In Molecular Medical Microbiology (Ed. M. Sussman) Academic Press: London.

 Riley, T.V., Brooke, C.J. and Wang, Q. 2001. Erysipelothrix rhusiopathiae. In Molecular Medical Microbiology (Ed. M Sussman) Academic Press: London.

 Riley, T.V. 2001. Alternative treatments for MRSA. In Infection Highlights 2000-2001. (Ed. M H Wilcox) Health Press: Oxford.

 Riley, T.V. 2002. Clostridium. In Medical Microbiology 16th Ed. (Eds. D. Greenwood, R. Slack and J. Peutherer) Churchill Livingstone: London.

J.-M. López-Lozano, D.L. Monnet, P. Campillos Alonso, A. Cabrera Quintero, N. Gonzalo Jiménez, A. Yagüe Muñoz, C. Thomas, A. Beyaert, M. Stevenson, T.V. Riley. 2004. Applications of time series analysis to antibiotic resistance and consumption data. In Antibiotic Policies, Theory and Practice. Gould, Ian M.; van der Meer, J.W. (Eds.) Springer: New York.

 Siarakas, S., Kewley, A. and Riley, T.V. 2005. Clostridium difficile. In A Compendium of Laboratory Methods for Common and Unusual Enteric Pathogens – an Australian Perspective. McIver, C.J. (ed.) ASM: Melbourne.

Riley, T.V. 2006. Clostridium. In Medical Microbiology 17th Ed. (Eds. D. Greenwood, R. Slack and J. Peutherer) Churchill Livingstone: London.

Riley, T.V. 2006. Alternative Therapies for MRSA (in press)

(b) Leading Articles, Reviews and Editorials

Carson, C.F. and Riley, T.V. 2001. Safety, efficacy and provenance of tea tree oil (Review). Contact Dermatitis 45: 65-67.

Riley, T.V. 2002. Topical antimicrobial therapy with tea tree oil - fact or fantasy (Review). Br J Infect Cont 3: 12-16.

Riley, T.V. 2002. 20 years of Clostridium difficile-associated diarrhoea - will it resolve? (Review) Aust J Med Sc 23: 156-161.

Riley, T.V. 2004. Nosocomial diarrhoea due to Clostridium difficile. Curr Opinions Infect Dis (Review) 17: 323-327.

Hammer, K.A., Carson, C.F. and Riley, T.V. 2005. Nature’s antiseptic (Review). Inform 16: 546-547.

Hammer, K.A., Carson, C.F., Riley, T.V. and Nielsen, J.B. 2006. A review of the toxicity of Melaleuca alternifolia (tea tree) oil (Review). Food Chem Toxicol 44: 616-625.

Carson, C.F., Hammer, K.A., and Riley, T.V. 2006. Melaleuca alternifolia (tea tree) oil: a review of antimicrobial and other medicinal properties (Review). Clin Microbiol Rev 19: 50-62.

Riley, T.V. 2006. Epidemic Clostridium difficile (Editorial). Med J Aust (in press)

(c) Journals

Cadwallader, H.L., Dyson, A. and Riley, T.V. 2002. A comparison of two methods of identifying surgical site infections following orthopaedic surgery. A reply. J Hosp Infect 49: 303-304.

 Hammer, K.A., Carson, C.F. and Riley, T.V. 2002. In vitro activity of Melaleuca alternifolia (tea tree) oil against dermatophytes and other filamentous fungi. J Antimicrob Chemother 50: 195-200.

 Wang, Q., Fidalgo, S., Chang, B.J., Mee, B.J. and Riley, T.V. 2002. The detection and recovery of Erysipelothrix spp. in meat and abattoir samples in Western Australia. J Appl Microbiol 92: 844-850.

 Carson, C.F., Mee, B.J. and Riley, T.V. 2002. Mechanism of action of Melaleuca alternifolia (tea tree) oil on Staphylococcus aureus determined by time-kill, lysis, leakage, loss of salt tolerance and electron microscopy. Antimicrob Agents Chemother 46: 1914-1920.

Fidalgo, S.G., Longbottom, C.J. and Riley, T.V. 2002. Susceptibility of Erysipelothrix rhusiopathiae to antimicrobial and home disinfectants. Pathology 34: 462-465.

 Thomas, C., Stevenson, M., Williamson, D.J. and Riley, T.V. 2002. Clostridium difficile-associated diarrhoea: epidemiological data from Western Australia following a change in antibiotic policy. Clin Infect Dis 35: 1457-1462.

 Thomas, C., Golledge, C.G. and Riley, T.V. 2002. Ciprofloxacin and Clostridium difficile-associated diarrhea. Infect Control Hosp Epidemiol 23: 637-638.

 Riley, T.V. 2002. Old therapies, new science. Microbiology Australia 23: 18-19.

 Coles, K., A., Knuiman, M.W., Plant, A.J., Riley, T.V., Smith, D.W. and Divitini, M. 2003. A prospective study of infection and cardiovascular diseases: the Busselton Health Study. Eur J Cardiovasc Prev Rehabil 10: 278-82.

Thomas, C. and Riley, T.V. 2003. Restriction of third generation cephalosporin use reduces the incidence of Clostridium difficile-associated diarrhoea in hospitalised patients. Comm Dis Intell 27 (Suppl): S28-S31.

 Carson, C.F. and Riley, T.V. 2003. Non-antibiotic therapies for infectious diseases. Comm Dis Intell 27 (Suppl): S144-S147.

 Brooke, C.J., Hampson, D.J. and Riley, T.V. 2003. In vitro antimicrobial susceptibility of human isolates of Brachyspira aalborgii. Antimicrob Agents Chemother 47: 2354-2357.

 Thomas, C., Stevenson, M. and Riley, T.V. 2003. Antibiotics and hospital-acquired Clostridium difficile-associated diarrhoea: a systematic review. J Antimicrob Chemother 51: 1339-1350.

 Brooke, C.J., Riley, T.V. and Hampson, D.J. 2003. Evaluation of selective media for the isolation of Brachyspira aalborgi from human faeces. J Med Microbiol 52: 509-513.

 Riley, T.V. and Golledge, C.L. 2003. Probiotics and Clostridium difficile-associated diarrhoea. Microbiol Aust 24: 20-21.

 Hammer, K.A., Dry, L., Johnson, M., Michalak, E.M., Carson, C.F. and Riley, T.V. 2003. Susceptibility of oral bacteria to Melaleuca alternifolia (tea tree) oil in vitro. Oral Microbiol Immunol 18: 389-392.

Unicomb, L., Ferguson, J., Riley, T.V. and Collignon, P. 2003. Fluoroquinolone resistance in Campylobacter absent from isolates, Australia. Emerg Infect Dis 9: 1482-1483.

 Su, L-H., Ou, J.T., Leu, H-S., Chiu, C-H., Chia, J-H., Kuo, A-J., Chiu, Y-P., Wu, T-l., Sun, C-F., Riley, T.V., Chang, B.J. and the Infection Control Team. 2003. Extended epidemic of nosocomial urinary tract infections caused by Serratia marcescens. J Clin Microbiol 41: 4726-4732.

 Hammer, K.A., Carson, C.F and Riley, T.V. 2003. Antifungal activity of the components of Melaleuca alternifolia (tea tree) oil. J Appl Microbiol 95: 853-860.

 Cordova, S.P., Heath, C.H., McGechie, D., Keil, A., Beers, M.Y. and Riley, T.V. 2004. Methicillin-resistant Staphylococcus aureus bacteraemia in Western Australian teaching hospitals, 1997-1999: Risk factors, outcomes and implications for management. J Hosp Infect 56: 22-28.

 Fidalgo. S. and Riley, T.V. 2004. Detection of Erysipelothrix rhusiopathiae in clinical and environmental samples. Methods Mol Biol 268:199-206.

 Thomas, C., Cadwallader, H. and Riley, T.V. 2004. Surgical site infections following orthopaedic surgery: statewide surveillance using linked administrative databases. J Hosp Infect 57: 25-30.

 Hammer, K.A., Carson, C.F. and Riley, T.V. 2004. Antifungal effects of Melaleuca alternifolia (tea tree) oil and its components on Candida albicans, Candida glabrata and Saccharomyces cerevisiae. J Antimicrob Chemother 53: 1081-5.

 Longbottom, C.J., Carson, C.F., Hammer, K.A., Mee, B.J. and Riley, T.V. 2004. Tolerance of Pseudomonas aeruginosa to Melaleuca alternifolia (tea tree) oil is associated with the outer membrane and energy dependent cellular processes. J Antimicrob Chemother 54: 386-92.

 Pirson, M., Dramaix, M., Struelens, M., Riley, T.V. and Leclercq, P. 2005. Costs associated with hospital-acquired bacteraemia in a Belgian hospital. J Hosp Infect 59: 33-40.

 Messager, S., Hammer, K.A., Carson, C.F. and Riley, T.V. 2005 Effectiveness of hand cleansing formulations containiing tea tree oil assessed ex-vivo, on human skin, and in-vivo with volunteers using European standard EN 1499. J Hosp Infect 59: 220-228.

 Messager, S., Hammer, K.A. Carson, C.F. and Riley, T.V. 2005. Assessment of the antibacterial activity of tea tree oil using the European EN 1276 and EN 12054 standard suspension tests. J Hosp Infect 59: 113-125.

 Goh, S., Riley, T.V. and Chang, B.J. 2005. Isolation and characterisation of temperate bacteriophages of Clostridium difficile. Appl Environ Microbiol 71: 1079-83.

 Goh, S., Chang, B.J. and Riley, T.V. 2005. Effect of phage infection on toxin production by Clostridium difficile. J Med Microbiol 54: 129-135.

 Wang, Q., Chang, B.J., Mee, B.J. and Riley, T.V. 2005. Neuraminidase production by Erysipelothrix rhusiopathiae. Veterinary Microbiology 107: 265-272.

 Dailey, L., Coombs, G., O’Brien, F., Pearman, J.W., Christiansen, K., Grubb, W.B. and Riley, T.V. 2005. Methicillin-resistant Staphylococcus aureus, Western Australia. Emerg Infect Dis 11: 1584-1590.

 Brooke, C.J., Riley, T.V. and Hampson, D.J. 2006. Comparison of prevalence and risk factors for faecal carriage of the intestinal spirochaetes Brachyspira aalborgi and Brachyspira pilosicoli in four Australian populations. Epidemiol Infect 134: 627-634.

 Watson, K., Carville, K., Bowman J., Jacoby, P., Riley, T.V., Leach, A.J. and Lehmann, D. for the Kalgoorlie Otitis Media Research Project Team. 2006. Upper respiratory tract bacterial carriage in Aboriginal and non-Aboriginal children in a semi-arid area of Western Australia. Ped Infect Dis J (accepted for publication March 2006)

 Papadopoulos, C., Carson, C. F.; Hammer K.A and Riley, T.V. 2006. Susceptibility of pseudomonads to Melaleuca alternifolia (tea tree) oil and components. J Antimicrob Chemother (accepted for publication 26 April 2006)

                                                                               

OTHER INTERESTS:

Music
Surfing
Historic and sports cars


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